Podiatric Medical News
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January 23, 2026 #8,190
Publisher-Barry Block, DPM, JD
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- People with higher levels of certain blood markers — including neutrophils, monocytes, and platelets compared to their HDL (“good”) cholesterol — were more likely to have diabetic foot ulcers.
- One marker, the monocyte-to-HDL ratio, was especially telling: if it went above a certain level (0.29), the chance of having a foot ulcer was more than four times higher.
- Low red blood cell levels may help explain part of the link between inflammation and foot ulcers, since red blood cells are important for wound healing.
- These simple blood test ratios might help doctors spot patients who need extra foot care or monitoring.
- The study looked at health data from over 1,200 U.S. adults with diabetes, using a national survey.
- More research is needed to confirm the results, figure out ideal cutoff values, and learn how best to use these markers in daily care.
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